node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPE0698 | CPE2276 | gene:10489960 | gene:10491584 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.704 |
CPE0698 | asd | gene:10489960 | gene:10491173 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.610 |
CPE0698 | dapA | gene:10489960 | gene:10491174 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.725 |
CPE0698 | dapB | gene:10489960 | gene:10491175 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.460 |
CPE0698 | dapF | gene:10489960 | gene:10491110 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.475 |
CPE0698 | dapG | gene:10489960 | gene:10490942 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | 398 aa, similar to gpu:AP001515_134 aspartokinase I (alpha and beta subunits) (EC 2.7.2.4) from Bacillus halodurans (411 aa); 46.5% identity in 396 aa overlap; CPE1678; Belongs to the aspartokinase family. | 0.688 |
CPE0698 | guaA | gene:10489960 | gene:10491583 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.703 |
CPE0698 | lysA | gene:10489960 | gene:10489856 | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.638 |
CPE2276 | CPE0698 | gene:10491584 | gene:10489960 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | 0.704 |
CPE2276 | asd | gene:10491584 | gene:10491173 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.429 |
CPE2276 | dapA | gene:10491584 | gene:10491174 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.446 |
CPE2276 | dapG | gene:10491584 | gene:10490942 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 398 aa, similar to gpu:AP001515_134 aspartokinase I (alpha and beta subunits) (EC 2.7.2.4) from Bacillus halodurans (411 aa); 46.5% identity in 396 aa overlap; CPE1678; Belongs to the aspartokinase family. | 0.406 |
CPE2276 | guaA | gene:10491584 | gene:10491583 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
CPE2276 | lysA | gene:10491584 | gene:10489856 | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.620 |
asd | CPE0698 | gene:10491173 | gene:10489960 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Hypothetical protein; 97 aa, similar to N-terminal of sp:PHEA_AQUAE P-PROTEIN [INCLUDES: CHORISMATE MUTASE (EC 5.4.99.5) (CM) from Aquifex aeolicus (362 aa); 30.1% identity in 93 aa overlap. | 0.610 |
asd | CPE2276 | gene:10491173 | gene:10491584 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Inositol-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.429 |
asd | dapA | gene:10491173 | gene:10491174 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.995 |
asd | dapB | gene:10491173 | gene:10491175 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.960 |
asd | dapD | gene:10491173 | gene:10491178 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Probable tetrahydrodipicolinate succinylase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.740 |
asd | dapF | gene:10491173 | gene:10491110 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.827 |