STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPE1817Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa)    
Predicted Functional Partners:
CPE1058
553 aa, similar to pir:D70680 hypothetical protein Rv2438c from Mycobacterium tuberculosis (strain H37RV) (738 aa); 42% identity in 581 aa overlap. 1 putative transmembrane region was found by PSORT; Belongs to the NAD synthetase family.
    
 0.966
CPE2125
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.940
CPE0256
Probable transcriptional regulator; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
 0.924
CPE1819
1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.901
CPE0594
Hypothetical protein; 157 aa, similar to C-terminal of gpu:AE004122_1 MutT/nudix family protein from Vibrio cholerae (269 aa); 32.1% identity in 162 aa overlap.
     
 0.900
hlyD
Probable hemolysin; 271 aa, similar to gpu:AP001516_207 hemolysin-like protein from Bacillus halodurans (272 aa); 56.1% identity in 262 aa overlap. 1 putative transmembrane region was found by PSORT; CPE1818.
  
  
 0.852
argR-2
Probable arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.845
recN
DNA repair and genetic recombination protein; May be involved in recombinational repair of damaged DNA.
  
  
 0.841
CPE1820
Geranyltranstransferase; 301 aa, similar to gpu:AP001516_210 geranyltranstransferase (EC 2.5.1.10) from Bacillus halodurans (294 aa); 43% identity in 286 aa overlap; Belongs to the FPP/GGPP synthase family.
 
 
 
 0.785
xseA
Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
     0.719
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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