STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheS341 aa, similar to sp:SYFA_BACSU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (EC 6.1.1.20) (PHENYLALANINE--TRNA LIGASE ALPHA CHAIN) (PHERS) from Bacillus subtilis (344 aa); 54% identity in 339 aa overlap; CPE1886; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (341 aa)    
Predicted Functional Partners:
pheT
phenylalanine-tRNA ligase beta chain; 793 aa, similar to gpu:AP001517_232 phenylalanyl-tRNA synthetase (EC 6.1.1.20) beta subunit from Bacillus halodurans (808 aa); 38.4% identity in 791 aa overlap. 1 putative transmembrane region was found by PSORT; CPE1885.
 
 0.999
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.990
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.755
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
  
 0.736
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.702
pnpA
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.700
CPE1884
Hypothetical protein; 451 aa, no significant homology.
       0.687
CPE1347
554 aa, similar to pir:B72341 uridine kinase-related protein from Thermotoga maritima (strain MSB8) (555 aa); 42.9% identity in 546 aa overlap.
  
 
 0.686
pyrF
287 aa, similar to gp:AF187997_1 orotidine-5'-monophosphate decarboxylase from Halobacterium salinarum (267 aa); 36.8% identity in 269 aa overlap; CPE1180; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.685
thrS
threonine-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
 
 
 0.671
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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