STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
podK876 aa, similar to sp:PODK_CLOSY PYRUVATE,PHOSPHATE DIKINASE (EC 2.7.9.1) (PYRUVATE,ORTHOPHOSPHATE DIKINASE) from Clostridium symbiosum (873 aa); 69.1% identity in 871 aa overlap; CPE2011; Belongs to the PEP-utilizing enzyme family. (876 aa)    
Predicted Functional Partners:
CPE2061
1171 aa, similar to gp:CPA17727_2 pyruvate ferredoxin oxidoreductase from Clostridium pasteurianum (1175 aa); 73.6% identity in 1167 aa overlap.
    
 0.981
pykA
Pyruvate kinase; 467 aa, similar to sp:KPYK_BACSU PYRUVATE KINASE (EC 2.7.1.40) (PK) (VEGETATIVE PROTEIN 17) (VEG17) from Bacillus subtilis (585 aa); 56% identity in 466 aa overlap. 1 putative transmembrane region was found by PSORT; CPE0362.
    
 0.969
pykA-3
Pyruvate kinase; 474 aa, similar to gpu:AP001517_285 pyruvate kinase (EC 2.7.1.40) from Bacillus halodurans (584 aa); 50% identity in 474 aa overlap; CPE2149.
    
 0.958
pykA-2
Probable pyruvate kinase; 364 aa, partially similar to gp:AE002118_3 pyruvate kinase from Ureaplasma urealyticum (474 aa); 31.5% identity in 324 aa overlap; CPE1025.
     
 0.957
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.940
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.926
CPE1151
Probable malate oxidoreductase; 381 aa, similar to pir:T46727 probable malic enzyme from Weissella paramesenteroides plasmid (378 aa); 49.1% identity in 373 aa overlap. 1 putative transmembrane region was found by PSORT; malic enzyme.
  
 
 0.924
ldhD
332 aa, similar to sp:LDHD_ECOLI D-LACTATE DEHYDROGENASE (EC 1.1.1.28) (D-LDH) from Escherichia coli (329 aa); 36.4% identity in 330 aa overlap; CPE0530; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.923
pflA
744 aa, similar to sp:PFL_CLOPA FORMATE ACETYLTRANSFERASE (EC 2.3.1.54) (PYRUVATE FORMATE-LYASE) from Clostridium pasteurianum (740 aa); 73.7% identity in 744 aa overlap. 1 putative transmembrane region was found by PSORT; CPE1153.
    
 0.916
CPE1094
Conserved hypothetical protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
  0.900
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.