node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPE0302 | CPE2432 | gene:10489558 | gene:10491750 | Hypothetical protein; 426 aa, no significant homology. Putative N-terminal signal sequence and 7 putative transmembrane regions were found by PSORT. | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.432 |
CPE1739 | CPE2432 | gene:10491003 | gene:10491750 | Probable protein phosphatase 1; 239 aa, similar to gpu:AP001515_239 BH2505 gene product from Bacillus halodurans (249 aa); 40.6% identity in 229 aa overlap. | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.459 |
CPE2430 | CPE2432 | gene:10491748 | gene:10491750 | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.433 |
CPE2430 | CPE2442 | gene:10491748 | gene:10491760 | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | Probable creatine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.449 |
CPE2430 | CPE2443 | gene:10491748 | gene:10491761 | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | Conserved hypothetical protein; 199 aa, similar to gp:LMU40604_2 Listeria monocytogenes ClpC ATPase (mec) gene, complete cds from Listeria monocytogenes (174 aa); 34% identity in 162 aa overlap. | 0.446 |
CPE2430 | ctsR | gene:10491748 | gene:10491762 | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | Transcriptional repressor of class III stress genes; 151 aa, similar to gp:AB031211_4 CtsR from Bacillus halodurans (156 aa); 38.3% identity in 149 aa overlap; CPE2444; Belongs to the CtsR family. | 0.505 |
CPE2430 | radA | gene:10491748 | gene:10491751 | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.560 |
CPE2432 | CPE0302 | gene:10491750 | gene:10489558 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Hypothetical protein; 426 aa, no significant homology. Putative N-terminal signal sequence and 7 putative transmembrane regions were found by PSORT. | 0.432 |
CPE2432 | CPE1739 | gene:10491750 | gene:10491003 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Probable protein phosphatase 1; 239 aa, similar to gpu:AP001515_239 BH2505 gene product from Bacillus halodurans (249 aa); 40.6% identity in 229 aa overlap. | 0.459 |
CPE2432 | CPE2430 | gene:10491750 | gene:10491748 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Conserved hypothetical protein; 368 aa, similar to gpu:AP001507_106 BH0106 gene product from Bacillus halodurans (362 aa); 47.7% identity in 367 aa overlap. Putative N-terminal signal sequence and 3 putative transmembrane regions were found by PSORT. | 0.433 |
CPE2432 | CPE2435 | gene:10491750 | gene:10491753 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Probable transcriptional regulator; 240 aa, similar to pir:D70044 transcription regulator GntR family homolog yvoA from Bacillus subtilis (243 aa); 37.3% identity in 225 aa overlap; GntR family. | 0.615 |
CPE2432 | CPE2442 | gene:10491750 | gene:10491760 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Probable creatine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family. | 0.494 |
CPE2432 | CPE2443 | gene:10491750 | gene:10491761 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Conserved hypothetical protein; 199 aa, similar to gp:LMU40604_2 Listeria monocytogenes ClpC ATPase (mec) gene, complete cds from Listeria monocytogenes (174 aa); 34% identity in 162 aa overlap. | 0.492 |
CPE2432 | clpC | gene:10491750 | gene:10491759 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | ClpC adenosine triphosphatase; 814 aa, similar to sp:CLPC_BACSU NEGATIVE REGULATOR OF GENETIC COMPETENCE CLPC/MECB from Bacillus subtilis (810 aa); 53.1% identity in 813 aa overlap; CPE2441; Belongs to the ClpA/ClpB family. | 0.455 |
CPE2432 | ctsR | gene:10491750 | gene:10491762 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Transcriptional repressor of class III stress genes; 151 aa, similar to gp:AB031211_4 CtsR from Bacillus halodurans (156 aa); 38.3% identity in 149 aa overlap; CPE2444; Belongs to the CtsR family. | 0.502 |
CPE2432 | nagB | gene:10491750 | gene:10491752 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.615 |
CPE2432 | radA | gene:10491750 | gene:10491751 | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.959 |
CPE2435 | CPE2432 | gene:10491753 | gene:10491750 | Probable transcriptional regulator; 240 aa, similar to pir:D70044 transcription regulator GntR family homolog yvoA from Bacillus subtilis (243 aa); 37.3% identity in 225 aa overlap; GntR family. | Conserved hypothetical protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.615 |
CPE2435 | nagB | gene:10491753 | gene:10491752 | Probable transcriptional regulator; 240 aa, similar to pir:D70044 transcription regulator GntR family homolog yvoA from Bacillus subtilis (243 aa); 37.3% identity in 225 aa overlap; GntR family. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.863 |
CPE2435 | radA | gene:10491753 | gene:10491751 | Probable transcriptional regulator; 240 aa, similar to pir:D70044 transcription regulator GntR family homolog yvoA from Bacillus subtilis (243 aa); 37.3% identity in 225 aa overlap; GntR family. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.644 |