Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolEMyo-inositol catabolism protein IolE; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). (297 aa)    
Predicted Functional Partners:
iolD
Myo-inositol catabolism protein IolD; Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
 
 
 0.998
CPF_0085
Myo-inositol 2-dehydrogenase; Identified by similarity to GB:AAC70005.1; match to protein family HMM PF01408; match to protein family HMM PF02894.
 
 
 0.993
CPF_0088
Oxidoreductase, Gfo/Idh/MocA family; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.
 
 
 0.989
CPF_0083
Putative myo-inositol catabolism protein IolB; Identified by similarity to SP:P42413; match to protein family HMM PF06845.
 
  
 0.971
iolC
Myo-inositol catabolism protein IolC; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
 
  
 0.905
CPF_0087
Identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.710
CPF_0081
Putative fructose-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167.
  
  
 0.614
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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