Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CPF_0146Cell wall surface anchor family protein; Identified by match to protein family HMM PF05737; match to protein family HMM PF05738; match to protein family HMM TIGR01167. (725 aa)    
Predicted Functional Partners:
CPF_0147
Putative surface protein; Identified by similarity to GB:AAO49409.1; match to protein family HMM PF05738.
 
     0.848
CPF_0122
Cna protein B-type domain protein; Identified by match to protein family HMM PF05738.
  
     0.695
CPF_0123
Cell wall surface anchor family protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167.
  
     0.565
CPF_0492
Identified by match to protein family HMM PF07170; match to protein family HMM TIGR03064.
 
 
   0.544
pfo
Perfringolysin O; Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A conformation change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host cell membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
  
     0.538
CPF_1467
Putative enterotoxin, EntA; Identified by similarity to GB:AAS44253.1; match to protein family HMM PF00018; match to protein family HMM PF08239.
  
     0.535
entD
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase domain protein, possible enterotoxin; Identified by match to protein family HMM PF00018; match to protein family HMM PF01832; match to protein family HMM PF06347; match to protein family HMM PF08239.
  
   
 0.485
CPF_0771
Cell wall surface anchor family protein; Identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167.
  
     0.476
CPF_0124
Identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076.
 
   
 0.450
CPF_0438
Conserved hypothetical protein; Identified by similarity to GB:AAT04397.1.
  
     0.450
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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