Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CPF_0238GGDEF/EAL domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254. (775 aa)    
Predicted Functional Partners:
CPF_1164
Putative sensory box-containing diguanylate cyclase; Identified by match to protein family HMM PF00990; match to protein family HMM PF01966; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
 
 
0.885
CPF_2043
GGDEF domain protein; Identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
 0.877
CPF_1220
GGDEF domain protein; Identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
 
 0.874
CPF_1264
Putative diguanylate cyclase; Identified by similarity to GB:AAC61683.1; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
  
0.733
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.684
CPF_0908
EAL domain protein; Identified by match to protein family HMM PF00563.
 
  
0.673
CPF_1243
Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229.
  
 
 0.649
CPF_0801
Sensory box protein/histidinol phosphate phosphatase family protein; Identified by similarity to SP:O34411; match to protein family HMM PF00990; match to protein family HMM PF02811; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; match to protein family HMM TIGR01856.
 
  
0.594
CPF_1064
EAL domain protein; Identified by similarity to SP:P32701; match to protein family HMM PF00563.
 
  
0.553
CPF_0106
Putative thiazole biosynthesis protein ThiH; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968.
  
  
 0.528
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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