node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_0143 | CPF_0239 | CPF_0143 | CPF_0239 | Hypothetical protein; Identified by glimmer; putative. | dnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.752 |
CPF_0143 | CPF_0240 | CPF_0143 | CPF_0240 | Hypothetical protein; Identified by glimmer; putative. | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | 0.533 |
CPF_0143 | CPF_0241 | CPF_0143 | CPF_0241 | Hypothetical protein; Identified by glimmer; putative. | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.809 |
CPF_0143 | clpB | CPF_0143 | CPF_1681 | Hypothetical protein; Identified by glimmer; putative. | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.555 |
CPF_0143 | clpC | CPF_0143 | CPF_2751 | Hypothetical protein; Identified by glimmer; putative. | Negative regulator of genetic competence MecB/ClpC; Identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; Belongs to the ClpA/ClpB family. | 0.555 |
CPF_0143 | dnaK | CPF_0143 | CPF_2290 | Hypothetical protein; Identified by glimmer; putative. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.809 |
CPF_0143 | grpE | CPF_0143 | CPF_2291 | Hypothetical protein; Identified by glimmer; putative. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.533 |
CPF_0239 | CPF_0143 | CPF_0239 | CPF_0143 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Hypothetical protein; Identified by glimmer; putative. | 0.752 |
CPF_0239 | CPF_0240 | CPF_0239 | CPF_0240 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | 0.937 |
CPF_0239 | CPF_0241 | CPF_0239 | CPF_0241 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.954 |
CPF_0239 | CPF_1497 | CPF_0239 | CPF_1497 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | ATPase domain protein; Identified by match to protein family HMM PF02518. | 0.752 |
CPF_0239 | clpB | CPF_0239 | CPF_1681 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.712 |
CPF_0239 | clpC | CPF_0239 | CPF_2751 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Negative regulator of genetic competence MecB/ClpC; Identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; Belongs to the ClpA/ClpB family. | 0.712 |
CPF_0239 | dnaK | CPF_0239 | CPF_2290 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.842 |
CPF_0239 | grpE | CPF_0239 | CPF_2291 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.748 |
CPF_0239 | hsp90 | CPF_0239 | CPF_0417 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Heat shock protein; Molecular chaperone. Has ATPase activity. | 0.752 |
CPF_0239 | nifJ | CPF_0239 | CPF_2318 | dnaJ domain protein; Identified by match to protein family HMM PF00226. | Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176. | 0.767 |
CPF_0240 | CPF_0143 | CPF_0240 | CPF_0143 | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | Hypothetical protein; Identified by glimmer; putative. | 0.533 |
CPF_0240 | CPF_0239 | CPF_0240 | CPF_0239 | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | dnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.937 |
CPF_0240 | CPF_0241 | CPF_0240 | CPF_0241 | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.961 |