nnrE protein (Clostridium perfringens ATCC 13124)

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nnrE

Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...] (499 aa)

Predicted Functional Partners:

acpS

0.969

groL

0.748

CPF_0286

0.745

CPF_2422

0.741

CPF_0289

0.727

CPF_0662

0.692

CPF_0882

0.692

CPF_2065

0.692

CPF_2150

0.692

CPF_0360

0.664

Your Current Organism:

Clostridium perfringens ATCC 13124

NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPF_0286	CPF_0289	CPF_0286	CPF_0289	Conserved hypothetical protein; Identified by similarity to PIR:A96960.	Conserved hypothetical protein; Identified by similarity to PIR:D96960.	0.623
CPF_0286	acpS	CPF_0286	CPF_0287	Conserved hypothetical protein; Identified by similarity to PIR:A96960.	Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	0.722
CPF_0286	nnrE	CPF_0286	CPF_0288	Conserved hypothetical protein; Identified by similarity to PIR:A96960.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.745
CPF_0289	CPF_0286	CPF_0289	CPF_0286	Conserved hypothetical protein; Identified by similarity to PIR:D96960.	Conserved hypothetical protein; Identified by similarity to PIR:A96960.	0.623
CPF_0289	acpS	CPF_0289	CPF_0287	Conserved hypothetical protein; Identified by similarity to PIR:D96960.	Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	0.702
CPF_0289	nnrE	CPF_0289	CPF_0288	Conserved hypothetical protein; Identified by similarity to PIR:D96960.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.727
CPF_0360	groL	CPF_0360	CPF_2573	Hypothetical protein; Identified by glimmer; putative.	Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.427
CPF_0360	nnrE	CPF_0360	CPF_0288	Hypothetical protein; Identified by glimmer; putative.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.664
CPF_0662	nnrE	CPF_0662	CPF_0288	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.692
CPF_0882	nnrE	CPF_0882	CPF_0288	Pyrophosphatase, MutT/nudix family; Identified by match to protein family HMM PF00293.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.692
CPF_2065	CPF_2150	CPF_2065	CPF_2150	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	0.926
CPF_2065	nnrE	CPF_2065	CPF_0288	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.692
CPF_2150	CPF_2065	CPF_2150	CPF_2065	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	0.926
CPF_2150	nnrE	CPF_2150	CPF_0288	Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.692
CPF_2422	nnrE	CPF_2422	CPF_0288	Conserved hypothetical protein TIGR00150; Identified by similarity to PIR:C97249; match to protein family HMM PF02367; match to protein family HMM TIGR00150.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.741
acpS	CPF_0286	CPF_0287	CPF_0286	Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	Conserved hypothetical protein; Identified by similarity to PIR:A96960.	0.722
acpS	CPF_0289	CPF_0287	CPF_0289	Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	Conserved hypothetical protein; Identified by similarity to PIR:D96960.	0.702
acpS	nnrE	CPF_0287	CPF_0288	Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.969
groL	CPF_0360	CPF_2573	CPF_0360	Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Hypothetical protein; Identified by glimmer; putative.	0.427
groL	nnrE	CPF_2573	CPF_0288	Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.748

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