Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_0423Identified by match to protein family HMM PF03372. (263 aa)    
Predicted Functional Partners:
CPF_0422
PTS system, IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02003.
 
  
 0.994
CPF_0421
Putative oligo-1,6-glucosidase; Identified by similarity to SP:P29094; match to protein family HMM PF00128.
  
 
 0.944
malQ
4-alpha-glucanotransferase; Identified by similarity to SP:P29851; match to protein family HMM PF02446; match to protein family HMM TIGR00217.
  
 
 0.935
CPF_0802
Glycosyl hydrolase, family 13; Identified by match to protein family HMM PF00128; match to protein family HMM PF02903; Belongs to the glycosyl hydrolase 13 family.
  
 
  0.906
CPF_0070
Putative PTS system, N-acetylglucosamine-specific IIA component; Identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830.
    
  0.905
CPF_2333
Alpha-glucosidase; Identified by similarity to SP:Q9F234; match to protein family HMM PF01055; Belongs to the glycosyl hydrolase 31 family.
     
  0.900
CPF_2648
Glycosyl hydrolase, family 31; Identified by match to protein family HMM PF01055; Belongs to the glycosyl hydrolase 31 family.
     
  0.900
plc
Phospholipase C; Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. Acts on human and mouse erythrocytes, but not on rabbit or horse erythrocytes.
   
  
 0.613
CPF_0796
Conserved hypothetical protein; Identified by similarity to SP:P28671.
  
     0.571
CPF_2336
Putative membrane protein.
 
     0.489
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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