Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_0499Sensor histidine kinase; Identified by match to protein family HMM PF02518. (431 aa)    
Predicted Functional Partners:
CPF_0498
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
 
  
 0.883
virR
DNA-binding response regulator VirR; Identified by similarity to GB:AAA58949.1; match to protein family HMM PF00072; match to protein family HMM PF04397.
 
  
 0.601
CPF_0512
Response regulator; Identified by match to protein family HMM PF00072.
  
 
 0.511
CPF_0500
Hypothetical protein; Identified by glimmer; putative.
       0.456
CPF_0497
Von Willebrand factor type A domain protein; Identified by match to protein family HMM PF00092.
       0.411
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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