Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CPF_0510Putative D-lactate dehydrogenase; Identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)    
Predicted Functional Partners:
CPF_0509
Transporter, auxin efflux carrier family; Identified by match to protein family HMM PF03547.
 
    0.880
nifJ
Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
     
 0.632
CPF_0511
Sensor histidine kinase; Identified by match to protein family HMM PF02518.
 
     0.618
CPF_0512
Response regulator; Identified by match to protein family HMM PF00072.
 
     0.615
CPF_0767
Iron-sulfur cluster-binding protein, rieske family; Identified by match to protein family HMM PF00355; match to protein family HMM PF01266.
   
  
 0.528
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.484
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family.
  
  
 0.478
nnrE
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
  
   0.470
tal
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
  
 0.457
CPF_1076
[Fe] hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00301; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM PF02915; match to protein family HMM TIGR02512.
   
 
 0.446
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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