Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CPF_0593Conserved domain protein. (201 aa)    
Predicted Functional Partners:
CPF_1073
Discoidin domain protein; Identified by match to protein family HMM PF00754; match to protein family HMM PF07554; match to protein family HMM PF08305.
  
     0.644
CPF_0540
Conserved hypothetical protein; Identified by similarity to GB:AAO35222.1.
  
    0.607
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.594
CPF_0796
Conserved hypothetical protein; Identified by similarity to SP:P28671.
  
     0.584
cobB-2
NAD-dependent deacetylase, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
    0.580
CPF_0110
Conserved hypothetical protein; Identified by similarity to GB:AAK76917.1.
  
     0.539
CPF_2336
Putative membrane protein.
  
     0.536
CPF_1133
Conserved domain protein; Identified by similarity to GB:AAP27300.1.
  
     0.532
CPF_1780
Putative lipoprotein.
  
     0.527
CPF_1489
F5/8 type C domain protein; Identified by match to protein family HMM PF00754; match to protein family HMM PF07554; match to protein family HMM PF08305.
  
     0.520
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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