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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AnSMEAnaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. (370 aa)    
Predicted Functional Partners:
CPF_0221
Sulfatase family protein; Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion.
 
  
 0.730
CPF_1101
Identified by match to protein family HMM PF00884.
 
  
 0.722
CPF_2199
Conserved hypothetical protein; Identified by similarity to GB:CAL84628.1.
   
   0.717
CPF_0615
Hypothetical protein; Identified by glimmer; putative.
       0.550
mdsC
Mucin-desulfating sulfatase; Identified by similarity to GB:AAF72522.1.
  
     0.519
pstS
Phosphate ABC transporter, phosphate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136.
       0.438
CPF_2198
Radical SAM domain protein; Identified by match to protein family HMM PF04055.
 
   
 0.432
CPF_2566
Putative type IV pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
    0.406
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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