node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AnSME | CPF_0221 | CPF_0616 | CPF_0221 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Sulfatase family protein; Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion. | 0.971 |
AnSME | CPF_0615 | CPF_0616 | CPF_0615 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Hypothetical protein; Identified by glimmer; putative. | 0.550 |
AnSME | CPF_1101 | CPF_0616 | CPF_1101 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Identified by match to protein family HMM PF00884. | 0.722 |
AnSME | CPF_2199 | CPF_0616 | CPF_2199 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Conserved hypothetical protein; Identified by similarity to GB:CAL84628.1. | 0.875 |
AnSME | CPF_2566 | CPF_0616 | CPF_2566 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Putative type IV pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. | 0.406 |
AnSME | mdsC | CPF_0616 | CPF_1410 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Mucin-desulfating sulfatase; Identified by similarity to GB:AAF72522.1. | 0.519 |
AnSME | pstS | CPF_0616 | CPF_0617 | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | Phosphate ABC transporter, phosphate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136. | 0.438 |
CPF_0221 | AnSME | CPF_0221 | CPF_0616 | Sulfatase family protein; Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.971 |
CPF_0221 | mdsC | CPF_0221 | CPF_1410 | Sulfatase family protein; Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion. | Mucin-desulfating sulfatase; Identified by similarity to GB:AAF72522.1. | 0.587 |
CPF_0615 | AnSME | CPF_0615 | CPF_0616 | Hypothetical protein; Identified by glimmer; putative. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.550 |
CPF_1101 | AnSME | CPF_1101 | CPF_0616 | Identified by match to protein family HMM PF00884. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.722 |
CPF_2199 | AnSME | CPF_2199 | CPF_0616 | Conserved hypothetical protein; Identified by similarity to GB:CAL84628.1. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.875 |
CPF_2566 | AnSME | CPF_2566 | CPF_0616 | Putative type IV pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.406 |
mdsC | AnSME | CPF_1410 | CPF_0616 | Mucin-desulfating sulfatase; Identified by similarity to GB:AAF72522.1. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.519 |
mdsC | CPF_0221 | CPF_1410 | CPF_0221 | Mucin-desulfating sulfatase; Identified by similarity to GB:AAF72522.1. | Sulfatase family protein; Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion. | 0.587 |
pstS | AnSME | CPF_0617 | CPF_0616 | Phosphate ABC transporter, phosphate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136. | Anaerobic sulfatase-maturating enzyme; Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM). Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological. | 0.438 |