Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
argHArgininosuccinate lyase; Identified by similarity to SP:O34858; match to protein family HMM PF00206; match to protein family HMM TIGR00838. (466 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.999
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.939
arcA
Arginine deiminase; Identified by match to protein family HMM PF02274; match to protein family HMM TIGR01078.
     
 0.922
purB
Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.920
CPF_0528
Orn/Lys/Arg decarboxylase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711.
     
 0.820
CPF_1222
Conserved domain protein.
  
  
 0.811
CPF_0581
Amino acid ABC transporter, amino acid-binding protein; Identified by match to protein family HMM PF00497; Belongs to the bacterial solute-binding protein 3 family.
  
  
 0.770
carB
Carbamoyl-phosphate synthase, large subunit; Identified by similarity to SP:P25994; match to protein family HMM PF00289; match to protein family HMM PF01071; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.
  
  
 0.710
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.682
argR-2
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.682
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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