Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dcm-2DNA-cytosine methyltransferase; Identified by similarity to SP:P20589; match to protein family HMM PF00145; match to protein family HMM TIGR00675. (446 aa)    
Predicted Functional Partners:
dcm
DNA-cytosine methyltransferase; Identified by similarity to GB:AAC98421.1; match to protein family HMM PF00145; match to protein family HMM TIGR00675.
 
 
0.977
CPF_0139
DNA-cytosine methyltransferase; Identified by similarity to SP:P23737; match to protein family HMM PF00145; match to protein family HMM TIGR00675.
  
  
 
0.927
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.915
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
  
  
  0.912
CPF_1475
Amidohydrolase domain protein; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
   
 
  0.903
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
mtnN-2
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
CPF_0978
Identified by match to protein family HMM PF01048.
     
  0.900
CPF_1016
Type II site-specific deoxyribonuclease; Possibly an isoschizomer of MboI found in Moraxella bovis; identified by similarity to GB:AAF75614.1; match to protein family HMM PF02976.
 
   
 0.676
CPF_0992
McrB domain protein; Identified by match to protein family HMM PF07728.
 
   
 0.409
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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