STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPF_1102Putative membrane protein; Identified by similarity to GB:AAO35944.1; match to protein family HMM PF01794. (229 aa)    
Predicted Functional Partners:
CPF_2364
Conserved hypothetical protein; Identified by similarity to GB:AAO36386.1; match to protein family HMM PF07550.
  
    0.774
CPF_0126
Identified by match to protein family HMM PF03595.
  
     0.684
pfo
Perfringolysin O; Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A conformation change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host cell membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
  
    0.619
CPF_0981
Conserved hypothetical protein; Identified by similarity to GB:CAA15293.1.
  
     0.596
hdc
Histidine decarboxylase, pyruvoyl type; Identified by match to protein family HMM PF02329; match to protein family HMM TIGR00541.
  
     0.588
CPF_1103
Glycosyl hydrolase, family 20; Identified by match to protein family HMM PF00728.
 
     0.555
CPF_2367
Major facilitator family transporter; Identified by match to protein family HMM PF07690.
  
     0.536
CPF_1226
Putative membrane protein.
  
     0.533
CPF_1189
Pentapeptide repeat protein; Identified by match to protein family HMM PF00805.
  
     0.494
CPF_0742
Conserved hypothetical protein; Identified by similarity to GB:CAJ70527.1.
  
     0.474
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.