Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_1338Transcriptional regulator, RpiR family; Identified by match to protein family HMM PF01380; match to protein family HMM PF01418. (291 aa)    
Predicted Functional Partners:
rluB
Ribosomal small subunit pseudouridine synthase B; Identified by similarity to SP:P35159; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family.
       0.758
CPF_1337
Conserved hypothetical protein; Identified by similarity to GB:CAD47129.1; match to protein family HMM PF06962.
       0.758
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
   
    0.614
fruA
PTS system, fructose-specific, IIABC component; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
     
 0.521
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
   
    0.518
cmk
Cytidylate kinase; Identified by similarity to SP:P38493; match to protein family HMM PF02224; match to protein family HMM TIGR00017.
       0.500
CPF_2168
Conserved hypothetical protein; Identified by similarity to PIR:A97194.
  
     0.472
CPF_1339
Pyridine nucleotide-disulphide oxidoreductase; Identified by match to protein family HMM PF00890; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275.
       0.471
CPF_2973
DHH family protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.466
CPF_2148
Conserved hypothetical protein; Identified by similarity to PIR:E97191.
  
     0.461
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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