Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pssACDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:P39823; match to protein family HMM PF01066; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (173 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 0.980
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by similarity to SP:P46322; match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.951
cdsA
Phosphatidate cytidylyltransferase; Identified by similarity to SP:O31752; match to protein family HMM PF01148; Belongs to the CDS family.
    
 0.927
tdcB
Threonine dehydratase, catabolic; Identified by similarity to SP:P05792; match to protein family HMM PF00291; match to protein family HMM PF01842; match to protein family HMM TIGR01127.
    
  0.902
sdhB
L-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
sdhA
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by similarity to SP:P33073; match to protein family HMM PF03313; match to protein family HMM TIGR00718; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
sdhB-2
L-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
sdhA-2
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by similarity to SP:P33073; match to protein family HMM PF03313; match to protein family HMM TIGR00718; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
cysE
Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.
    
  0.805
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
Server load: low (22%) [HD]