node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_0426 | CPF_2238 | CPF_0426 | CPF_2238 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | 0.568 |
CPF_0426 | CPF_2416 | CPF_0426 | CPF_2416 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | Identified by match to protein family HMM PF00149. | 0.545 |
CPF_0426 | mutL | CPF_0426 | CPF_1359 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.747 |
CPF_0426 | pcrA | CPF_0426 | CPF_2542 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | ATP-dependent DNA helicase PcrA; Identified by similarity to SP:P56255; match to protein family HMM PF00580; match to protein family HMM TIGR01073. | 0.937 |
CPF_0426 | polA | CPF_0426 | CPF_2250 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.848 |
CPF_0426 | recA | CPF_0426 | CPF_1927 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.797 |
CPF_0426 | recQ-2 | CPF_0426 | CPF_1542 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.625 |
CPF_0426 | sbcD | CPF_0426 | CPF_0206 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | Putative nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.545 |
CPF_0426 | topA | CPF_0426 | CPF_1956 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.818 |
CPF_0426 | topB | CPF_0426 | CPF_1760 | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.818 |
CPF_2238 | CPF_0426 | CPF_2238 | CPF_0426 | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.568 |
CPF_2238 | pcrA | CPF_2238 | CPF_2542 | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | ATP-dependent DNA helicase PcrA; Identified by similarity to SP:P56255; match to protein family HMM PF00580; match to protein family HMM TIGR01073. | 0.403 |
CPF_2238 | polA | CPF_2238 | CPF_2250 | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.616 |
CPF_2238 | recA | CPF_2238 | CPF_1927 | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.577 |
CPF_2238 | recQ-2 | CPF_2238 | CPF_1542 | DNA topoisomerase; Identified by match to protein family HMM PF01131; match to protein family HMM PF01751. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.697 |
CPF_2416 | CPF_0426 | CPF_2416 | CPF_0426 | Identified by match to protein family HMM PF00149. | Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.545 |
CPF_2416 | pcrA | CPF_2416 | CPF_2542 | Identified by match to protein family HMM PF00149. | ATP-dependent DNA helicase PcrA; Identified by similarity to SP:P56255; match to protein family HMM PF00580; match to protein family HMM TIGR01073. | 0.410 |
CPF_2416 | polA | CPF_2416 | CPF_2250 | Identified by match to protein family HMM PF00149. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.987 |
CPF_2416 | recA | CPF_2416 | CPF_1927 | Identified by match to protein family HMM PF00149. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.590 |
CPF_2416 | recQ-2 | CPF_2416 | CPF_1542 | Identified by match to protein family HMM PF00149. | ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. | 0.602 |