Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pcpPyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. (213 aa)    
Predicted Functional Partners:
CPF_1679
Putative membrane protein; Identified by match to protein family HMM PF06166.
 
    0.942
CPF_1680
Conserved hypothetical protein; Identified by similarity to GB:AAM24813.1; match to protein family HMM PF06149.
 
     0.937
CPF_1677
Conserved hypothetical protein; Identified by similarity to GB:AAM24816.1; match to protein family HMM PF06094.
 
     0.854
CPF_2611
Conserved hypothetical protein; Identified by similarity to GB:AAO36364.1.
   
   0.814
CPF_1992
Identified by match to protein family HMM PF00481.
    
   0.808
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.790
CPF_2245
Conserved hypothetical protein; Identified by similarity to PIR:H97195.
  
   0.683
CPF_0239
dnaJ domain protein; Identified by match to protein family HMM PF00226.
   
   0.655
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.655
CPF_1170
Putative glycerol uptake facilitator protein; Identified by similarity to SP:P18156; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.644
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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