STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDuroporphyrinogen-III methyltransferase/synthase; Identified by similarity to GB:AAK00606.1; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469. (492 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.
 
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
CPF_1689
Identified by match to protein family HMM TIGR01470.
 
 
 0.996
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.983
cobI
Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
 
 0.977
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.
 
  
 0.956
CPF_0526
Nitrite/sulfite reductase homolog; Identified by similarity to GB:BAA06530.1; match to protein family HMM PF01077; match to protein family HMM PF03460; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.944
cobJ
precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466.
  
 0.780
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Identified by match to protein family HMM PF05175; match to protein family HMM TIGR02469.
 
  
 0.776
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.762
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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