Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_1867Identified by match to protein family HMM PF01551. (441 aa)    
Predicted Functional Partners:
CPF_0297
Putative cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.752
ftsE
Putative cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
  
 0.747
pbpA
Penicillin-binding protein, 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
  
 0.711
CPF_1562
Identified by match to protein family HMM PF00877; match to protein family HMM PF06347; match to protein family HMM PF07653; match to protein family HMM PF08239.
  
  
 0.637
CPF_0274
SagA protein; Identified by similarity to GB:AAF86217.1; match to protein family HMM PF00877.
  
  
 0.617
CPF_1755
3D/G5 domain protein; Identified by match to protein family HMM PF03990; match to protein family HMM PF06725; match to protein family HMM PF07501.
 
  
 0.568
CPF_2842
3D/G5 domain protein; Identified by match to protein family HMM PF03990; match to protein family HMM PF06725; match to protein family HMM PF07501.
 
  
 0.555
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
   
 0.541
CPF_1866
Hypothetical protein; Identified by glimmer; putative.
       0.496
CPF_0880
LysM domain protein; Identified by match to protein family HMM PF01476.
  
  
 0.475
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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