Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CPF_1872ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00580. (763 aa)    
Predicted Functional Partners:
pcrA
ATP-dependent DNA helicase PcrA; Identified by similarity to SP:P56255; match to protein family HMM PF00580; match to protein family HMM TIGR01073.
 
  
 0.931
CPF_0580
Conserved hypothetical protein; Identified by similarity to GB:ABR36889.1.
  
  
 
0.921
CPF_1416
Putative ATP-dependent DNA helicase PcrA; Identified by similarity to SP:Q53727; match to protein family HMM PF00580.
 
  
 0.917
CPF_0426
Identified by match to protein family HMM PF00580; match to protein family HMM PF00929; match to protein family HMM TIGR00573.
    
 0.909
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.815
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.806
CPF_1871
Conserved hypothetical protein; Identified by similarity to GB:AAM24475.1; match to protein family HMM PF06949; Belongs to the UPF0473 family.
       0.750
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.739
CPF_1870
Conserved hypothetical protein; Identified by similarity to PIR:D97030.
       0.726
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.691
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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