CPF_1916 protein (Clostridium perfringens ATCC 13124)

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Score

CPF_1916

Identified by match to protein family HMM PF02541. (502 aa)

Predicted Functional Partners:

relA

0.928

CPF_0635

0.911

guaB

0.573

polA

0.445

folBK

0.406

guaA

0.406

Your Current Organism:

Clostridium perfringens ATCC 13124

NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPF_0635	CPF_1916	CPF_0635	CPF_1916	Identified by match to protein family HMM PF04607.	Identified by match to protein family HMM PF02541.	0.911
CPF_0635	relA	CPF_0635	CPF_2193	Identified by match to protein family HMM PF04607.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.919
CPF_1916	CPF_0635	CPF_1916	CPF_0635	Identified by match to protein family HMM PF02541.	Identified by match to protein family HMM PF04607.	0.911
CPF_1916	folBK	CPF_1916	CPF_1277	Identified by match to protein family HMM PF02541.	Dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.	0.406
CPF_1916	guaA	CPF_1916	CPF_2557	Identified by match to protein family HMM PF02541.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.406
CPF_1916	guaB	CPF_1916	CPF_2558	Identified by match to protein family HMM PF02541.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.573
CPF_1916	polA	CPF_1916	CPF_2250	Identified by match to protein family HMM PF02541.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.445
CPF_1916	relA	CPF_1916	CPF_2193	Identified by match to protein family HMM PF02541.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.928
folBK	CPF_1916	CPF_1277	CPF_1916	Dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.	Identified by match to protein family HMM PF02541.	0.406
guaA	CPF_1916	CPF_2557	CPF_1916	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Identified by match to protein family HMM PF02541.	0.406
guaA	guaB	CPF_2557	CPF_2558	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	polA	CPF_2557	CPF_2250	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.805
guaA	relA	CPF_2557	CPF_2193	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.416
guaB	CPF_1916	CPF_2558	CPF_1916	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Identified by match to protein family HMM PF02541.	0.573
guaB	guaA	CPF_2558	CPF_2557	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.999
guaB	polA	CPF_2558	CPF_2250	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.617
guaB	relA	CPF_2558	CPF_2193	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.489
polA	CPF_1916	CPF_2250	CPF_1916	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	Identified by match to protein family HMM PF02541.	0.445
polA	guaA	CPF_2250	CPF_2557	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.805
polA	guaB	CPF_2250	CPF_2558	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.617