STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (491 aa)    
Predicted Functional Partners:
spoIIID
Stage III sporulation protein D; Identified by similarity to SP:P15281; match to protein family HMM TIGR02844.
  
  
 0.879
CPF_2087
Stage III sporulation protein AA; Identified by match to protein family HMM TIGR02858.
  
  
 0.870
CPF_2297
Stage II sporulation protein P; Identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867.
 
   
 0.867
CPF_2084
Stage III sporulation protein AD; Identified by match to protein family HMM PF09555; match to protein family HMM TIGR02849.
  
    0.859
CPF_2475
Stage II sporulation protein R; Identified by similarity to SP:P39151; match to protein family HMM PF09551; match to protein family HMM TIGR02837.
  
   
 0.855
spo0A
Spo0A protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.852
spoIID
Stage II sporulation protein D; Identified by similarity to SP:P07372; match to protein family HMM PF08486; match to protein family HMM TIGR02669; match to protein family HMM TIGR02870.
  
  
 0.848
CPF_2081
Stage III sporulation protein AG; Identified by match to protein family HMM TIGR02830.
  
  
 0.844
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.844
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.839
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.