Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2009Conserved hypothetical protein; Identified by similarity to PIR:A97111; match to protein family HMM PF04459. (445 aa)    
Predicted Functional Partners:
engA
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
    0.885
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase family protein; Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF03721; match to protein family HMM PF03807; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.837
CPF_2011
Conserved hypothetical protein; Identified by similarity to PIR:F97109; match to protein family HMM PF02578; Belongs to the multicopper oxidase YfiH/RL5 family.
     
 0.598
CPF_2010
Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
  
    0.572
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
       0.565
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.472
CPF_1401
Conserved hypothetical protein; Identified by similarity to PIR:AF1870.
  
     0.447
CPF_2387
Conserved hypothetical protein; Identified by similarity to GB:AAO36563.1.
  
     0.442
CPF_2013
PRC-barrel domain protein; Identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888.
       0.412
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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