Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2013PRC-barrel domain protein; Identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888. (90 aa)    
Predicted Functional Partners:
spoIIGA
Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
     0.857
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.831
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.770
CPF_2083
Stage III sporulation protein AE; Identified by match to protein family HMM PF09546; match to protein family HMM TIGR02829.
  
     0.747
CPF_2475
Stage II sporulation protein R; Identified by similarity to SP:P39151; match to protein family HMM PF09551; match to protein family HMM TIGR02837.
 
     0.727
ytxC
Putative sporulation protein YtxC; Identified by similarity to PIR:D97191; match to protein family HMM PF08812; match to protein family HMM TIGR02834.
  
   
 0.708
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.703
CPF_2058
Conserved hypothetical protein; Identified by similarity to GB:AAO36078.1; match to protein family HMM PF09579; match to protein family HMM TIGR02874.
  
  
 0.702
yunB
Sporulation protein YunB; Identified by similarity to PIR:T44346; match to protein family HMM PF09560; match to protein family HMM TIGR02832.
  
   
 0.702
CPF_2086
Stage III sporulation protein AB; Identified by similarity to SP:Q01368; match to protein family HMM PF09548; match to protein family HMM TIGR02833.
  
     0.691
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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