STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIGASporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (268 aa)    
Predicted Functional Partners:
spoIIE
Stage II sporulation protein E; Identified by similarity to SP:P37475; match to protein family HMM PF07228; match to protein family HMM TIGR02865.
  
  
 0.944
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.934
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.926
CPF_2475
Stage II sporulation protein R; Identified by similarity to SP:P39151; match to protein family HMM PF09551; match to protein family HMM TIGR02837.
 
   
 0.885
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.882
CPF_2297
Stage II sporulation protein P; Identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867.
  
   
 0.862
CPF_2013
PRC-barrel domain protein; Identified by match to protein family HMM PF05239; match to protein family HMM TIGR02888.
 
     0.856
spoIIID
Stage III sporulation protein D; Identified by similarity to SP:P15281; match to protein family HMM TIGR02844.
  
  
 0.852
spoIIM
Stage II sporulation protein M; Identified by similarity to SP:P37873; match to protein family HMM PF01944; match to protein family HMM TIGR02831.
  
  
 0.824
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
  
 0.812
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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