Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilTTwitching motility protein PilT; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420. (350 aa)    
Predicted Functional Partners:
CPF_2571
Type IV leader peptidase family protein; Identified by match to protein family HMM PF01478; match to protein family HMM PF06750.
 
   
 0.860
CPF_2097
Putative pilus biogenesis protein; Identified by similarity to GB:AAA25733.1; match to protein family HMM PF00482.
 
  
 0.824
CPF_2569
Bacterial type II secretion system protein F; Identified by match to protein family HMM PF00482.
 
  
 0.824
CPF_2565
Type IV pilus assembly protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.
 
   
 0.819
CPF_2568
Putative type IV pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
 
  
 0.693
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
     
 0.684
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
       0.671
CPF_2021
RNA polymerase sigma-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.606
CPF_2022
Putative penicillin-binding protein; Identified by match to protein family HMM PF00905.
  
    0.543
spoIIGA
Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
       0.498
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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