node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_0339 | CPF_2022 | CPF_0339 | CPF_2022 | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | 0.714 |
CPF_0339 | mraY | CPF_0339 | CPF_2114 | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.736 |
CPF_0339 | murC | CPF_0339 | CPF_2816 | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.804 |
CPF_0339 | murF | CPF_0339 | CPF_2115 | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.713 |
CPF_0339 | pbpA | CPF_0339 | CPF_2218 | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | Penicillin-binding protein, 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.566 |
CPF_2021 | CPF_2022 | CPF_2021 | CPF_2022 | RNA polymerase sigma-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | 0.750 |
CPF_2021 | mltG | CPF_2021 | CPF_2026 | RNA polymerase sigma-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.555 |
CPF_2022 | CPF_0339 | CPF_2022 | CPF_0339 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | Cell cycle protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | 0.714 |
CPF_2022 | CPF_2021 | CPF_2022 | CPF_2021 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | RNA polymerase sigma-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.750 |
CPF_2022 | mltG | CPF_2022 | CPF_2026 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.701 |
CPF_2022 | mraY | CPF_2022 | CPF_2114 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.646 |
CPF_2022 | murC | CPF_2022 | CPF_2816 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.647 |
CPF_2022 | murE | CPF_2022 | CPF_2116 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.676 |
CPF_2022 | murF | CPF_2022 | CPF_2115 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.674 |
CPF_2022 | pbpA | CPF_2022 | CPF_2218 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | Penicillin-binding protein, 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.783 |
CPF_2022 | rodA | CPF_2022 | CPF_2391 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | Rod shape-determining protein RodA; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; Belongs to the SEDS family. | 0.864 |
CPF_2022 | spoVE | CPF_2022 | CPF_2113 | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | Stage V sporulation protein E; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615; Belongs to the SEDS family. | 0.866 |
mltG | CPF_2021 | CPF_2026 | CPF_2021 | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | RNA polymerase sigma-70 factor family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.555 |
mltG | CPF_2022 | CPF_2026 | CPF_2022 | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | Putative penicillin-binding protein; Identified by match to protein family HMM PF00905. | 0.701 |
mltG | pbpA | CPF_2026 | CPF_2218 | Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | Penicillin-binding protein, 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.568 |