Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2040Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738. (153 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.952
nifU
FeS cluster assembly scaffold protein NifU; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR03419.
 
  
 0.937
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.794
CPF_1667
Aminotransferase, class V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212.
 
  
 0.739
nifJ
Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
     
 0.622
CPF_1441
Conserved hypothetical protein.
  
  
 0.579
CPF_2036
PRC-barrel domain protein; Identified by match to protein family HMM PF05239.
       0.553
CPF_1269
Rubredoxin/flavodoxin/oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00258; match to protein family HMM PF00301; match to protein family HMM PF00753; match to protein family HMM PF07992.
   
 
 0.529
CPF_0538
Glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; Identified by match to protein family HMM PF00528; match to protein family HMM PF04069.
     
 0.417
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
Server load: low (22%) [HD]