Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CPF_2173Voltage-gated chloride channel family protein; Identified by match to protein family HMM PF00654; match to protein family HMM PF02080. (519 aa)    
Predicted Functional Partners:
CPF_2143
Potassium uptake protein, TrkH family; Identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933.
  
 
 0.766
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.692
nifJ
Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
  
 
 0.674
hemD
uroporphyrinogen-III methyltransferase/synthase; Identified by similarity to GB:AAK00606.1; match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469.
  
  
 0.579
CPF_0671
Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857.
 
  
 0.541
folC
FolC bifunctional protein; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
       0.515
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.487
CPF_0728
Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992.
 
  
 0.477
cinA
cinA family protein; Identified by similarity to SP:P46323; match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.
 
  
 0.465
CPF_0534
Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
  
 0.460
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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