CPF_2183 protein (Clostridium perfringens ATCC 13124)

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Score

CPF_2183

Identified by match to protein family HMM PF01244. (320 aa)

Predicted Functional Partners:

CPF_2182

0.654

nifJ

0.557

glyA

0.505

CPF_2239

0.441

cinA

0.406

Your Current Organism:

Clostridium perfringens ATCC 13124

NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPF_2182	CPF_2183	CPF_2182	CPF_2183	Identified by similarity to SP:P51831; match to protein family HMM PF00106.	Identified by match to protein family HMM PF01244.	0.654
CPF_2182	glyA	CPF_2182	CPF_2184	Identified by similarity to SP:P51831; match to protein family HMM PF00106.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.404
CPF_2183	CPF_2182	CPF_2183	CPF_2182	Identified by match to protein family HMM PF01244.	Identified by similarity to SP:P51831; match to protein family HMM PF00106.	0.654
CPF_2183	CPF_2239	CPF_2183	CPF_2239	Identified by match to protein family HMM PF01244.	Putative amidohydrolase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.	0.441
CPF_2183	cinA	CPF_2183	CPF_0130	Identified by match to protein family HMM PF01244.	cinA family protein; Identified by similarity to SP:P46323; match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.	0.406
CPF_2183	glyA	CPF_2183	CPF_2184	Identified by match to protein family HMM PF01244.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.505
CPF_2183	nifJ	CPF_2183	CPF_2318	Identified by match to protein family HMM PF01244.	Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.557
CPF_2239	CPF_2183	CPF_2239	CPF_2183	Putative amidohydrolase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.	Identified by match to protein family HMM PF01244.	0.441
cinA	CPF_2183	CPF_0130	CPF_2183	cinA family protein; Identified by similarity to SP:P46323; match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.	Identified by match to protein family HMM PF01244.	0.406
cinA	glyA	CPF_0130	CPF_2184	cinA family protein; Identified by similarity to SP:P46323; match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.406
glyA	CPF_2182	CPF_2184	CPF_2182	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Identified by similarity to SP:P51831; match to protein family HMM PF00106.	0.404
glyA	CPF_2183	CPF_2184	CPF_2183	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Identified by match to protein family HMM PF01244.	0.505
glyA	cinA	CPF_2184	CPF_0130	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	cinA family protein; Identified by similarity to SP:P46323; match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.	0.406
glyA	nifJ	CPF_2184	CPF_2318	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.719
nifJ	CPF_2183	CPF_2318	CPF_2183	Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	Identified by match to protein family HMM PF01244.	0.557
nifJ	glyA	CPF_2318	CPF_2184	Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.719