Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CPF_2248Transglycosylase, SLT family; Identified by match to protein family HMM PF01464. (181 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.870
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.837
CPF_2247
Glycosyl hydrolase, family 8; Identified by match to protein family HMM PF01270.
       0.702
CPF_1986
Conserved hypothetical protein; Identified by similarity to GB:AAO35798.1; match to protein family HMM PF03780.
   
    0.569
glsA-2
Glutaminase; Identified by match to protein family HMM PF04960; Belongs to the glutaminase family.
       0.551
CPF_2395
Putative penicillin-binding protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
 
  
 0.550
mltG
Conserved hypothetical protein TIGR00247; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
  
 0.512
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
   
 0.495
CPF_0880
LysM domain protein; Identified by match to protein family HMM PF01476.
  
  
 0.492
pbpA
Penicillin-binding protein, 1A family; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
   
 0.438
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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