Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CPF_2274Identified by similarity to SP:P19638; match to protein family HMM PF01219; match to protein family HMM PF01569. (232 aa)    
Predicted Functional Partners:
ybeY
Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
 0.978
cdsA
Phosphatidate cytidylyltransferase; Identified by similarity to SP:O31752; match to protein family HMM PF01148; Belongs to the CDS family.
    
 0.920
CPF_0710
Putative monogalactosyldiacylglycerol synthase; Identified by match to protein family HMM PF04101; match to protein family HMM PF06925.
  
 
  0.908
plsD
Sn-glycerol-3-phosphate acyltransferase; Identified by similarity to GB:AAC46006.1; match to protein family HMM PF01553.
    
 0.908
CPF_1671
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    
 0.908
CPF_2470
Putative monogalactosyldiacylglycerol synthase; Identified by match to protein family HMM PF04101; match to protein family HMM PF06925.
  
 
  0.908
plc
Phospholipase C; Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. Acts on human and mouse erythrocytes, but not on rabbit or horse erythrocytes.
     
  0.900
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase family protein; Identified by similarity to SP:P46919; match to protein family HMM PF01210; match to protein family HMM PF03721; match to protein family HMM PF03807; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.847
CPF_2276
Putative hydrolase; Identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277.
 
     0.825
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.806
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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