STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (325 aa)    
Predicted Functional Partners:
CPF_2297
Stage II sporulation protein P; Identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867.
 
  
 0.915
spoVAD
Stage V sporulation protein AD; Identified by similarity to SP:P40869; match to protein family HMM PF07451; match to protein family HMM TIGR02845.
  
  
 0.914
spoVAC
Stage V sporulation protein AC; Identified by match to protein family HMM PF03862; match to protein family HMM TIGR02838.
  
  
 0.872
spo0A
Spo0A protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.835
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.834
yyaC
Putative sporulation protein YyaC; Identified by similarity to PIR:E97251; match to protein family HMM PF06866; match to protein family HMM TIGR02841.
  
  
 0.834
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.824
yyaC-2
Putative sporulation protein YyaC; Identified by similarity to GB:AAO34757.1; match to protein family HMM PF06866; match to protein family HMM TIGR02841.
  
  
 0.813
CPF_2068
Stage IV sporulation protein B; Identified by match to protein family HMM PF05580; match to protein family HMM TIGR02860.
  
    0.811
spoVT
Stage V sprulation protein T; Identified by similarity to SP:P37554; match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851.
  
  
 0.802
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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