Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2345Sensor histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580. (578 aa)    
Predicted Functional Partners:
CPF_2344
DNA-binding response regulator, AraC family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
 
 
 0.994
CPF_1111
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00072; match to protein family HMM PF00165.
 
 
 0.965
CPF_1112
Sensor histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF06580.
  
  
 
0.928
CPF_0554
Sensor histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580.
  
  
 
0.927
CPF_0498
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
 
  
 0.787
CPF_2346
Putative membrane protein.
 
  
 0.770
virR
DNA-binding response regulator VirR; Identified by similarity to GB:AAA58949.1; match to protein family HMM PF00072; match to protein family HMM PF04397.
 
  
 0.764
CPF_2335
Bacterial extracellular solute-binding protein; Identified by similarity to SP:P37966; match to protein family HMM PF01547.
 
   
 0.723
CPF_1077
Bacterial extracellular solute-binding protein; Identified by match to protein family HMM PF01547.
 
   
 0.714
CPF_1285
Conserved hypothetical protein; Identified by similarity to PIR:D83749; match to protein family HMM PF01547.
 
   
 0.713
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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