Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
minDSeptum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968. (265 aa)    
Predicted Functional Partners:
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
 
 0.999
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
 
 0.995
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
    0.826
mreD
Rod shape-determining protein MreD; Identified by match to protein family HMM TIGR03426.
  
  
 0.821
mreB
Rod shape-determining protein MreB; Identified by match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904.
  
 
 0.725
rodA
Rod shape-determining protein RodA; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; Belongs to the SEDS family.
  
  
 0.637
CPF_2395
Putative penicillin-binding protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
     
 0.557
CPF_2399
DNA repair protein, RadC family; Identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
    0.555
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
    0.515
CPF_2389
Peptidase, M50 family; Identified by match to protein family HMM PF02163.
       0.507
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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