Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mreBRod shape-determining protein MreB; Identified by match to protein family HMM PF02491; match to protein family HMM PF06723; match to protein family HMM TIGR00904. (342 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.990
CPF_2395
Putative penicillin-binding protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
 
 
 
 0.956
mreD
Rod shape-determining protein MreD; Identified by match to protein family HMM TIGR03426.
  
  
 0.913
rodA
Rod shape-determining protein RodA; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; Belongs to the SEDS family.
 
 
 0.909
CPF_2399
DNA repair protein, RadC family; Identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
  
 0.888
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.750
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.742
minD
Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968.
  
 
 0.725
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.685
spoVE
Stage V sporulation protein E; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; match to protein family HMM TIGR02615; Belongs to the SEDS family.
 
 
 0.613
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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