Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2473Conserved hypothetical protein; Identified by similarity to GB:AAO34936.1; match to protein family HMM PF09148. (139 aa)    
Predicted Functional Partners:
CPF_2474
Thiamin biosynthesis protein ThiI; Identified by match to protein family HMM PF02568.
       0.787
CPF_2475
Stage II sporulation protein R; Identified by similarity to SP:P39151; match to protein family HMM PF09551; match to protein family HMM TIGR02837.
       0.696
argS
arginyl-tRNA synthetase; Identified by similarity to SP:P11875; match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.
  
    0.686
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.622
ispE
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
    0.595
CPF_2190
Putative ferrochelatase; Identified by similarity to SP:P32396; match to protein family HMM PF04055.
   
    0.553
CPF_2254
Conserved hypothetical protein; Identified by similarity to GB:AAO35390.1.
  
     0.536
cphA
Cyanophycin synthetase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR02068; Belongs to the MurCDEF family.
  
    0.509
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
   
    0.504
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.459
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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