Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crt3-hydroxybutyryl-CoA dehydratase; Identified by similarity to SP:P52046; match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)    
Predicted Functional Partners:
hbd
3-hydroxybutyryl-CoA dehydrogenase; Identified by similarity to SP:P52041; match to protein family HMM PF00725; match to protein family HMM PF02737.
 0.999
bcd
butyryl-CoA dehydrogenase; Identified by similarity to SP:P52042; match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
 
 0.996
CPF_2460
acetyl-CoA acetyltransferase; Identified by similarity to SP:P45359; match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
 0.991
CPF_0092
butyryl-CoA dehydrogenase; Identified by similarity to SP:P52042; match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
 
 0.985
fabV
Alcohol dehydrogenase, short-chain family; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family.
   
 
 0.910
CPF_0090
3-hydroxybutyryl-CoA dehydratase; Identified by similarity to SP:P52046; match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 
0.902
CPF_2583
Electron transfer flavoprotein, beta subunit/FixA family protein; Identified by match to protein family HMM PF01012.
  
 
 0.887
CPF_2582
Electron transfer flavoprotein, alpha subunit/FixB family protein; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012.
 
 
 0.811
rex
DNA-binding protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
     
 0.748
rpsB
30S ribosomal protein S2; Identified by similarity to SP:P21464; match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.
   
 0.704
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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