Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dacAConserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (285 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.949
CPF_2659
Conserved hypothetical protein; Identified by similarity to PIR:G97278; match to protein family HMM PF07949.
 
  
 0.945
CPF_2127
Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880.
   
 
 0.812
CPF_2658
Conserved hypothetical protein; Identified by similarity to PIR:F97278; match to protein family HMM PF01266; match to protein family HMM PF07992.
       0.684
CPF_2661
Conserved hypothetical protein; Identified by similarity to PIR:A97279.
       0.651
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.612
CPF_2662
Putative spore-cortex-lytic enzyme; Identified by similarity to SP:P50739; match to protein family HMM PF07486.
       0.564
CPF_2276
Putative hydrolase; Identified by match to protein family HMM PF01966; match to protein family HMM PF07697; match to protein family HMM PF07698; match to protein family HMM TIGR00277.
 
  
 0.534
ptb
Phosphate butyryltransferase; Identified by similarity to SP:Q05624; match to protein family HMM PF01515; match to protein family HMM TIGR02706.
       0.531
buk
Butyrate kinase; Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate; Belongs to the acetokinase family.
       0.515
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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