Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPF_2803Identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444. (483 aa)    
Predicted Functional Partners:
spoVB-3
Stage V sporulation protein B; Identified by match to protein family HMM PF01943; match to protein family HMM PF03023.
  
    0.775
CPF_2801
S4 domain protein; Identified by match to protein family HMM PF01479.
  
    0.739
hup
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
     
 0.616
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.591
spoVT
Stage V sprulation protein T; Identified by similarity to SP:P37554; match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851.
       0.569
CPF_1527
Putative iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF08331.
  
     0.525
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
     
 0.519
yabP
Sporulation protein YabP; Identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892.
  
    0.509
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.500
yabQ
Spore cortex biosynthesis protein YabQ; Identified by similarity to PIR:E97294; match to protein family HMM TIGR02893.
  
    0.491
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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