Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
prsA-2Putative foldase protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (342 aa)    
Predicted Functional Partners:
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.665
spoVT
Stage V sprulation protein T; Identified by similarity to SP:P37554; match to protein family HMM PF04014; match to protein family HMM TIGR01439; match to protein family HMM TIGR02851.
       0.601
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
     
 0.595
cspC
Serine protease C; Identified by similarity to GB:BAB60713.1; match to protein family HMM PF00082.
   
 
 0.534
nifJ
Pyruvate-flavodoxin oxidoreductase; Identified by similarity to SP:P19543; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
   
 
 0.506
spoVB-3
Stage V sporulation protein B; Identified by match to protein family HMM PF01943; match to protein family HMM PF03023.
       0.488
CPF_2803
Identified by match to protein family HMM PF00590; match to protein family HMM PF03819; match to protein family HMM TIGR00444.
       0.472
hup
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
  
  
 0.464
yabQ
Spore cortex biosynthesis protein YabQ; Identified by similarity to PIR:E97294; match to protein family HMM TIGR02893.
 
     0.458
oxaA
Membrane protein OxaA; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592.
 
  
 0.449
Your Current Organism:
Clostridium perfringens ATCC 13124
NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124
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