CPF_2809 protein (Clostridium perfringens ATCC 13124)

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Score

CPF_2809

PDZ domain protein; Identified by match to protein family HMM PF00595. (385 aa)

Predicted Functional Partners:

glpK

0.650

mfd

0.549

pth

0.529

rplK

0.516

rplT

0.513

pnpA

0.491

rpsF

0.460

clpP

0.447

CPF_0859

0.438

polA

0.432

Your Current Organism:

Clostridium perfringens ATCC 13124

NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPF_0859	CPF_2809	CPF_0859	CPF_2809	Identified by match to protein family HMM PF00041; match to protein family HMM PF00754; match to protein family HMM PF05089; match to protein family HMM PF07554.	PDZ domain protein; Identified by match to protein family HMM PF00595.	0.438
CPF_0859	polA	CPF_0859	CPF_2250	Identified by match to protein family HMM PF00041; match to protein family HMM PF00754; match to protein family HMM PF05089; match to protein family HMM PF07554.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.964
CPF_2809	CPF_0859	CPF_2809	CPF_0859	PDZ domain protein; Identified by match to protein family HMM PF00595.	Identified by match to protein family HMM PF00041; match to protein family HMM PF00754; match to protein family HMM PF05089; match to protein family HMM PF07554.	0.438
CPF_2809	clpP	CPF_2809	CPF_1647	PDZ domain protein; Identified by match to protein family HMM PF00595.	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.447
CPF_2809	glpK	CPF_2809	CPF_2876	PDZ domain protein; Identified by match to protein family HMM PF00595.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.650
CPF_2809	mfd	CPF_2809	CPF_2807	PDZ domain protein; Identified by match to protein family HMM PF00595.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.549
CPF_2809	pnpA	CPF_2809	CPF_1934	PDZ domain protein; Identified by match to protein family HMM PF00595.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.491
CPF_2809	polA	CPF_2809	CPF_2250	PDZ domain protein; Identified by match to protein family HMM PF00595.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.432
CPF_2809	pth	CPF_2809	CPF_2808	PDZ domain protein; Identified by match to protein family HMM PF00595.	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	0.529
CPF_2809	rplK	CPF_2809	CPF_2726	PDZ domain protein; Identified by match to protein family HMM PF00595.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.516
CPF_2809	rplT	CPF_2809	CPF_2144	PDZ domain protein; Identified by match to protein family HMM PF00595.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.513
CPF_2809	rpsF	CPF_2809	CPF_2978	PDZ domain protein; Identified by match to protein family HMM PF00595.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.460
clpP	CPF_2809	CPF_1647	CPF_2809	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	PDZ domain protein; Identified by match to protein family HMM PF00595.	0.447
clpP	polA	CPF_1647	CPF_2250	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.661
clpP	rplK	CPF_1647	CPF_2726	ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.498
glpK	CPF_2809	CPF_2876	CPF_2809	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	PDZ domain protein; Identified by match to protein family HMM PF00595.	0.650
mfd	CPF_2809	CPF_2807	CPF_2809	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	PDZ domain protein; Identified by match to protein family HMM PF00595.	0.549
mfd	polA	CPF_2807	CPF_2250	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.725
mfd	pth	CPF_2807	CPF_2808	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	0.913
pnpA	CPF_2809	CPF_1934	CPF_2809	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	PDZ domain protein; Identified by match to protein family HMM PF00595.	0.491