node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPF_2811 | glmU | CPF_2811 | CPF_2813 | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | 0.522 |
CPF_2811 | prsA | CPF_2811 | CPF_2812 | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.572 |
CPF_2811 | purR | CPF_2811 | CPF_2815 | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Pur operon repressor; Identified by similarity to SP:P37551; match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743. | 0.415 |
CPF_2811 | spoVG | CPF_2811 | CPF_2814 | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | Stage V sporulation protein G; Could be involved in septation. | 0.444 |
clpX | groL | CPF_1646 | CPF_2573 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.609 |
clpX | spoVG | CPF_1646 | CPF_2814 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Stage V sporulation protein G; Could be involved in septation. | 0.520 |
glmU | CPF_2811 | CPF_2813 | CPF_2811 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.522 |
glmU | murC | CPF_2813 | CPF_2816 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.774 |
glmU | prsA | CPF_2813 | CPF_2812 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.943 |
glmU | purR | CPF_2813 | CPF_2815 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | Pur operon repressor; Identified by similarity to SP:P37551; match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743. | 0.717 |
glmU | spoVG | CPF_2813 | CPF_2814 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | Stage V sporulation protein G; Could be involved in septation. | 0.650 |
groL | clpX | CPF_2573 | CPF_1646 | Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.609 |
groL | rpoB | CPF_2573 | CPF_2722 | Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.552 |
groL | spoVG | CPF_2573 | CPF_2814 | Chaperonin, GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Stage V sporulation protein G; Could be involved in septation. | 0.446 |
murC | glmU | CPF_2816 | CPF_2813 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | 0.774 |
murC | prsA | CPF_2816 | CPF_2812 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.428 |
murC | purR | CPF_2816 | CPF_2815 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Pur operon repressor; Identified by similarity to SP:P37551; match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743. | 0.613 |
murC | spoVG | CPF_2816 | CPF_2814 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Stage V sporulation protein G; Could be involved in septation. | 0.472 |
prsA | CPF_2811 | CPF_2812 | CPF_2811 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.572 |
prsA | glmU | CPF_2812 | CPF_2813 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] | 0.943 |