STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN97_13035Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.934
CN97_06865
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.891
CN97_12430
Redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.891
CN97_04070
Redox-active disulfide protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.886
CN97_19755
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.854
hflX
GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
      0.798
CN97_06230
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.713
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.687
CN97_16140
RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
  
 0.640
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
   
 
 0.636
Your Current Organism:
Haematobacter massiliensis
NCBI taxonomy Id: 195105
Other names: CCUG 47968, CIP 107725, H. massiliensis, Haematobacter massiliensis Heisel et al. 2007, Rhodobacter massiliensis, Rhodobacter massiliensis Greub and Raoult 2006, cf. Rhodobacter sp. Framboise, strain Framboise
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.