STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BD01_0070Putative dehydrogenase; COG0579. (495 aa)    
Predicted Functional Partners:
BD01_0069
Putative NAD(FAD)-dependent dehydrogenase; COG0446.
     0.993
BD01_0068
Uncharacterized protein with conserved CXXC pairs; COG3862.
 
    0.957
egsA
Glycerol dehydrogenase-related enzyme; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
    
  0.901
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
  
 0.728
BD01_1549
Putative NAD(FAD)-dependent dehydrogenase; COG0446.
   
 0.505
BD01_0076
Glycerophosphoryl diester phosphodiesterase; COG0584.
 
   
 0.499
BD01_0077
Glycerophosphoryl diester phosphodiesterase; COG0584.
 
   
 0.498
BD01_0071
Putative nucleic acid-binding protein, contains PIN domain; COG1848.
       0.491
BD01_0072
Hypothetical protein.
       0.483
BD01_0078
Permeases of the major facilitator superfamily; COG0477.
     
 0.410
Your Current Organism:
Thermococcus nautili
NCBI taxonomy Id: 195522
Other names: CNCM 4275, JCM 19601, T. nautili, Thermococcus nautili Gorlas et al. 2014, Thermococcus nautilus, Thermococcus sp. 30-1, strain 30-1
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